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| Modern Genetic Analysis Chapter 16. The Genetic Basis of Development Forming Complex Pattern: Establishing Positional Information Figure 16-16. The distribution of DL in response to the SPZ signal [encoded by the spaetzle (spz) gene]. A cross section of the cellular blastoderm-stage Drosophila embryo is depicted, with the dorsal midline at the top and the ventral midline at the bottom. Note that the DL protein is in the nucleus ventrally, throughout the cell laterally, and in the cytoplasm dorsally. (Adapted from S. Roth, D. Stein, and C. Nüsslein-Volhard, Cell 59, 1989, 1196.)

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