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Modern Genetic Analysis Chapter 14. Regulation of Gene Transcription Regulation of the Lactose System
Table 14-1. Synthesis of b-Galactosidase and Permease in Haploid and Heterozygous Diploid Operator Mutants

|  | b-GALACTOSIDASE (Z) | PERMEASE (Y) |

Strain | Genotype | Noninduced | Induced | Noninduced | Induced | Conclusions

1 | O+Z+Y+ |  | + |  | + | Wild type is inducible
2 | O+Z+Y+/F O+ZY+ |  | + |  | + | Z+ is dominant to Z
3 | OcZ+Y+ | + | + | + | + | Oc is constitutive
4 | O+ZY+/F OcZ+Y | + | + |  | + | Operator is cis-acting

NOTE: Bacteria were grown in glycerol (no glucose present) with and without the inducer IPTG. The presence or absence of enzyme is indicated by + or , respectively. All strains are I+.

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