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| Modern Genetic Analysis Chapter 15. Regulation of Cell Number: Normal and Cancer Cells Controlling the Cell Proliferation and Death Machinery Figure 15-11. One pathway for RTK signaling. Raf, MEK, and MAP kinase are three cytoplasmic protein kinases that are sequentially activated in the signal transduction cascade. (Adapted from H. Lodish, D. Baltimore, A. Berk, S. L. Zipursky, P. Matsudaira, and J. Darnell, Molecular Cell Biology, 3d ed. Copyright © 1995 by Scientific American Books.)

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