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| Modern Genetic Analysis Chapter 3. Gene Function Protein Function and Malfunction in Cells Figure 3-24. The active site of the digestive enzyme carboxypeptidase. (a) The enzyme without substrate. (b) The enzyme with its substrate (gold) in position. Three crucial amino acids (red) have changed positions to move closer to the substrate. Carboxypeptidase carves up proteins in the diet. (From W. N. Lipscomb, Proceedings of the Robert A. Welch Foundation Conferences on Chemical Research 15, 1971, 140141.)

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