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| Modern Genetic Analysis Chapter 7. Gene Mutations The Molecular Basis of Mutation Figure 7-15. Deletions in lacI. Deletions occurring in S74 and S112 are shown at the top of the diagram. As indicated by the gold bars, one of the sequence repeats (green) and all the intervening DNA has been deleted, leaving one copy of the repeated sequence. All mutations were analyzed by direct DNA sequence determination. (From P. J. Farabaugh, U. Schmeissner, M. Hofer, and J. H. Miller, Journal of Molecular Biology 126, 1978, 847.)

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