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| Modern Genetic Analysis Chapter 2. The Structure of Genes and Genomes The Nature of Eukaryotic Nuclear Chromosomes Figure 2-19. (a) Model of a nucleosome showing the DNA wrapped twice around a histone octamer. (Alan Wolffe and Van Moudrianakis.) (b) Two views of a model of the 30-nm solenoid showing histone octamers as purple disks. (Left) Partially unwound lateral view. (Right) End view. The additional histone H1 is shown running down the center of the coil, probably acting as a stabilizer. With increasing salt concentrations, the nucleosomes close up to form a solenoid with six nucleosomes per turn. (From H. Lodish, D. Baltimore, A. Berk, S. L. Zipursky, P. Matsudaira, and J. Darnell, Molecular Cell Biology, 3d ed. Copyright © 1995 by Scientific American Books.)

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