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| Modern Genetic Analysis Chapter 12. Genomics Functional Genomics Figure 12-33. The architecture of the genome of the bacterium Hemophilus influenzae, based on the complete genomic sequence reported in 1995. The circles have the following meanings, starting with the outer circle: Restriction sites and genomic positions, starting from the NotI site Genes color coded by their functional groups (see key) Regions of high G·C content: red > 42%; blue > 40%. Regions of high A·T content: black > 66%; green > 64%. Coverage of some clones used in sequencing Ribosomal operons (green), tRNAs (black), m -like prophage (blue) Positions of simple tandem repeats Replication origins (green arrows) and termination sequences (red) (Illustration by Dr. Anthony R. Kerlavage; Institute for Genomic Research. From Science, 1995, 269, 449604.)

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