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| Modern Genetic Analysis Chapter 14. Regulation of Gene Transcription Regulation of the Lactose System Figure 14-8. O+ / Oc heterozygotes demonstrate that operators are cis-acting. Because a repressor cannot bind to Oc operators, the lac structural genes linked to an Oc operator are expressed even in the absence of an inducer. However, the lac genes adjacent to an O+ operator are still subject to repression.

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