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| Modern Genetic Analysis Chapter 7. Gene Mutations The Molecular Basis of Mutation Figure 7-24. Repair of AP (apurinic or apyrimidinic) sites. AP endonucleases recognize AP sites and cut the phosphodiester bond. A stretch of DNA is removed by an exonuclease, and the resulting gap is filled in by DNA polymerase I and DNA ligase. (After B. Lewin, Genes. Copyright © 1983 by John Wiley.)

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