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| Modern Genetic Analysis Chapter 9. The Genetics of Bacteria and Phages Bacterial Conjugation Figure 9-9. Circularity of the E. coli chromosome. (a) Through the use of different Hfr strains (H, 1, 2, 3, 312) that have the fertility factor inserted into the chromosome at different points and in different directions, interrupted-mating experiments indicate that the chromosome is circular. The mobilization point (origin) is shown for each strain. (b) The linear order of transfer of markers for each Hfr strain; arrowheads indicate the origin and direction of transfer.

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