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| Modern Genetic Analysis Chapter 16. The Genetic Basis of Development The Many Parallels in Vertebrate and Insect Pattern Formation Figure 16-31. Comparisons of the structures and functions of the insect and mammalian homeotic genes. (a) The comparative anatomy of the HOM-C and Hox gene clusters. The genes of the HOM-C are shown at the top. Each of the four paralogous (see text) Hox clusters maps on a different chromosome. Genes shown in the same color are most closely related to one another in structure and function. (b) The expression domains and regions of the Drosophila and mouse embryos that require the various HOM-C and Hox genes. The color scheme parallels that in part a. Note that the order of domains in the two embryos is the same. (Adapted from H. Lodish, D. Baltimore, A. Berk, S. L. Zipursky, P. Matsudaira, and J. Darnell, Molecular Cell Biology, 3d ed. Copyright © Scientific American Books, 1995.)

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