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Modern Genetic Analysis Further Readings
Chapter 10
R. J. Britten and D. Kohne. 1968. Repeated Sequences in DNA Science 161: 529-540. One of the important summaries of the theoretical basis for distinguishing DNAs by renaturation. (PubMed)
Broda, P. 1979. Plasmids. New York: W. H. Freeman and Company. One of the few technical books on the subject.
D. D. Brown. 1973. The Isolation of Genes Scientific American August. Illustrates the power of focusing molecular techniques on one specific locus with special properties. (PubMed)
S. Cohen. 1975. The Manipulation of Genes Scientific American July. A summary of recombinant DNA techniques by one of the main innovators.
J. M. Fernández-Cañón et al. 1996. The Molecular Basis of Alkaptonuria Nature Genetics 14: 19-24. A description of the cloning of the aku gene. (PubMed)
J. C. Fiddes. 1977. The Nucleotide Sequence of a Viral DNA Scientific American December. This is a review of a landmark, the DNA sequence of an entire virus genome with an unexpected discovery. (PubMed)
W. Gilbert and L. Villa-Komaroff. 1980. Useful Proteins from Recombinant Bacteria Scientific American April. A description of the method of DNA sequencing used most extensively. Also discusses the potential application of recombinant DNA techniques. (PubMed)
K. Itakura et al. 1977. Expression in E. coli of a Chemically Synthesized Gene for the Hormone Somatostatin Science 198: 1056-1063. A technical paper well worth reading for its historical significance. It represents the start of bioengineeringusing DNA manipulation to modify cells to produce a medically useful human protein. (PubMed)
H. G. Khorana et al. 1972. Studies on Polynucleotides. CIII. Total Synthesis of the Structural Gene for an Alanine Transfer Ribonucleic Acid from Yeast Journal of Molecular Biology 72: 209-217. A classic technical paper. (PubMed)
K. B. Mullis. 1990. The Unusual Origin of the Polymerase Chain Reaction Scientific American April. An account by the discoverer of the PCR. (PubMed)
D. Nathans and H. O. Smith. 1975. Restriction Endonucleases in the Analysis and Restructuring of DNA Molecules Annual Review of Biochemistry 44: 273-293. A technical review of restriction enzymes by two pioneers in the field. (PubMed)
Sambrook, J., E. F. Fritsch, and T. Maniatis. 1989. Molecular Cloning, 2d ed. Cold Spring Harbor, NY: Cold Spring Harbor Laboratory Press. A practical manual found in all genetics research laboratories.
C. R. Scriver. 1996. Alkaptonuria: Such a Long Journey Nature Genetics 14: 5-6. An interesting commentary on the genetics of this inborn error of metabolism. (PubMed)
R. L. Sinsheimer. 1977. Recombinant DNA Annual Review of Biochemistry 46: 415-438. A provocative article by a leading molecular biologist who expressed concern about potential hazards of DNA manipulation. (PubMed)
H. Varmus. 1987. Reverse Transcription Scientific American September. (PubMed)
Watson, J. D., M. Gilman, J. Witkowski, and M. Zoller. 1992. Recombinant DNA, 2d ed. New York: W. H. Freeman and Company. A well-written account of recombinant DNA and its applications, with many wonderful illustrations.

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