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| Modern Genetic Analysis Chapter 11. Applications of Recombinant DNA Technology Gene Therapy Figure 11-21. The rat growth hormone gene (RGH), under the control of a mouse promoter region that is responsive to heavy metals, is inserted into a plasmid and used to produce a transgenic mouse. RGH compensates for the inherent dwarfism (lit / lit) in the mouse. RGH is inherited in a Mendelian dominant pattern in the ensuing mouse pedigree.

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