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| Modern Genetic Analysis Chapter 16. The Genetic Basis of Development Additional Aspects of Pattern Formation Figure 16-27. Two types of positive feedback loops in maintaining the level of activity of transcription factors determining cell fate. (a) The transcription factor binds to an enhancer of its own gene, maintaining its transcription. (b) Each adjacent cell sends out a signal (different signals from each cell) that activates receptors, signal transduction pathways, and transcription-factor (TF) expression in the other cell. This activation leads to a mutual positive feedback loop between the cells.

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