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Modern Genetic Analysis Chapter 15. Regulation of Cell Number: Normal and Cancer Cells Cancer: the Genetics of Aberrant Cell Control
Table 15-1. The Relations between Function of the Wild-Type Protein Product and the Types of Tumor-Promoting Mutations That Can Arise in the Genes Encoding Those Products

Type of wild-type protein function | Properties of tumor-promoting mutations

Promotes cell cycle progression | Oncogene (gain of function)
Inhibits cell cycle progression | Tumor-suppressor gene (loss of function)
Promotes apoptosis | Tumor-suppressor gene (loss of function)
Inhibits apoptosis | Oncogene (gain of function)
Promotes DNA repair | Tumor-suppressor gene (loss of function)

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