Book Viewer

Short Contents | Full Contents | Other books @ NCBI

Modern Genetic Analysis Chapter 7. Gene Mutations
Solved Problem

3. | Explain why mutations induced by acridines in phage T4 or by ICR-191 in bacteria cannot be reverted by 5-bromouracil. See answer

| Solution Acridines and ICR-191 induce mutations by deleting or adding one or more base pairs, which results in a frameshift. However, 5-bromouracil induces mutations by causing the substitution of one base for another. This substitution cannot compensate for the frameshift resulting from ICR-191 and acridines. See question

© 1999 by W. H. Freeman and Company. All rights reserved.