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| Modern Genetic Analysis Chapter 9. The Genetics of Bacteria and Phages Bacterial Conjugation Figure 9-10. Mapping by recombination in E. coli. After a cross, selection is made for the leu+ marker, which is donated late. The early markers (arg+ and met+) may or may not be inserted, depending on the site where recombination between the Hfr fragment and the F chromosome occurs.

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