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| Modern Genetic Analysis Chapter 7. Gene Mutations The Molecular Basis of Mutation Figure 7-19. Sequences of wild-type (WT) mitochondrial DNA and of deleted DNA (KS) from a patient with Kearns-Sayre/chronic external opthalmoplegia plus syndrome. The 13-base boxed sequence is identical in both WT and KS and serves as a breakpoint for the DNA deletion. A single base (boldface type) is altered in KS, aside from the deleted segment.

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